Keynote Address: On Target: Neural Mechanisms of Therapeutic Change
This session offers 1 CE credit.
Olu Ajilore, M.D., Ph.D.
University of Illinois-Chicago
On Target: Neural Mechanisms of Therapeutic Change
This talk will review the use of problem-solving treatment and for multimorbid conditions, namely depression and obesity exploring the findings from the mechanistic ENGAGE and ENGAGE-2 studies. Then we will discuss how these findings informed the development of a voice-enabled, AI-based therapy coach to deliver PST for participants with mild-to-moderate depression and/or anxiety. Finally, the promise and peril of using AI therapy chatbots will be discussed with a review of evaluation frameworks for digital therapeutics.
Category: Translational, Neuroscience / Neuroimaging, Treatment - Other
Keyword: Translational Research, Neuroscience, Treatment
All levels of familiarity with the material
Participants earn 1 continuing education credit
Outline:
- Introduction to problem-solving therapy
- ENGAGE study findings - efficacy and mechanisms
- ENGAGE-2 study findings - efficacy and mechanisms
- Introduction to voice-enabled, AI-based therapy coach to deliver problem-solving therapy
- Intervention development
- RCT findings
- Discussion of AI therapy chatbots
- Advantages, challenges, and ethical considerations for use of AI therapy chatbots
- Review of evaluation frameworks for digital therapeutics
At the end of this session, the learner will be able to:
- Describe therapeutic mechanism(s) of problem-solving therapy for multimorbid conditions, specifically depression and obesity.
- Describe the development and efficacy of a voice-enabled, AI-based therapy coach for problem-solving therapy in depression and anxiety.
- Evaluate potential advantages and drawbacks of using AI-based therapy coaches for mental health care.
1-2 Long Term Goals for the Attendee (takeaways)
- Develop a foundational understanding of neural circuits that may be associated with cognitive-behavioral therapies.
- Develop a foundational understanding of the use of AI in mental health treatment, including opportunities for enhancing treatment, related challenges, and ethical considerations.
Recommended Readings:
- Lv, N., Ajilore, O. A., Xiao, L., Venditti, E. M., Lavori, P. W., Gerber, B. S., ... & Ma, J. (2023). Mediating effects of neural targets on depression, weight, and anxiety outcomes of an integrated collaborative care intervention: the engage-2 mechanistic pilot randomized clinical trial. Biological Psychiatry Global Open Science, 3(3), 430-442.
- Kannampallil, T., Ajilore, O. A., Lv, N., Smyth, J. M., Wittels, N. E., Ronneberg, C. R., ... & Ma, J. (2023). Effects of a virtual voice-based coach delivering problem-solving treatment on emotional distress and brain function: a pilot RCT in depression and anxiety. Translational psychiatry, 13(1), 166.
- Obradovich, N., Khalsa, S. S., Khan, W. U., Suh, J., Perlis, R. H., Ajilore, O., & Paulus, M. P. (2024). Opportunities and risks of large language models in psychiatry. NPP—Digital Psychiatry and Neuroscience, 2(1), 8.
This session offers 1 CE credit. All attendees will receive a certificate of completion when the course requirements are satisfied. Certificates of completion is included in the cost of the summit
ABCT is approved by the American Psychological Association to sponsor continuing education for psychologists. ABCT maintains responsibility for this program and its content
The Association for Behavioral and Cognitive Therapies has been approved by NBCC as an Approved Continuing Education Provider, ACEP No. 5797. Programs that do not qualify for NBCC credit are clearly identified. The Association for Behavioral and Cognitive Therapies is solely responsible for all aspects of the programs
The Association for Behavioral and Cognitive Therapies is recognized by the California Board of Behavioral Sciences for Marriage and Family Therapist (MFT) to offer continuing education as Provider #4600
Association for Behavioral and Cognitive Therapies (ABCT), is recognized by the New York State Education Department’s State Board for Psychology as an approved provider of continuing education for licensed psychologists #PSY-0124
Association for Behavioral and Cognitive Therapies (ABCT), is recognized by the New York State Education Department’s State Board for Social Workers as an approved provider of continuing education for licensed social workers #SW-0657